Ignite Creation Date:
2024-05-06 @ 4:07 PM
Last Modification Date:
2024-10-26 @ 2:04 PM
Study NCT ID:
NCT04875143
Status:
UNKNOWN
Last Update Posted:
2021-05-06
First Post:
2021-04-30
Brief Title:
Effects Of Acute Supplementation Of Citrus Aurantium L On The Recovery Of Autonomic And Cardiovascular Activity After A Sub-Maximum Aerobic Exercise Session In Healthy Individuals
Sponsor:
University of Pernambuco
Organization:
University of Pernambuco
Study Overview
Official Title:
Effects Of Acute Supplementation Of Citrus Aurantium L On The Recovery Of Autonomic And Cardiovascular Activity After A Submitted Aerobic Exercise Session In Healthy Individuals A Prospective Randomizado-Plato-Rudomizado Plado Study
Status:
UNKNOWN
Status Verified Date:
2021-04
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
INTRODUCTION Non-pharmacological interventions for the treatment of cardiovascular and metabolic disorders have been investigated In this context Citrus aurantium L popularly known as Bitter Orange rich in synephrine p-synephrine a phenylethylaminic alkaloid that is present in the bitter orange peel has been used as an adjunct in metabolic disorders Given the effects the components of Citrus aurantium L diverge from other thermogens by being able to activate metabolism and lipolysis without interfering with the performance of the cardiovascular system making this an advantage for its use in diets In studies it has been observed that the activation of β-3 receptors plays an important role in the regulation and activation of other receptors modulating and when they are stimulated in excess and thus it presents effects that in addition to not causing overload in the cardiovascular system OBJECTIVE To evaluate the effect of supplementation of Citrus aurantium L in combination with submaximal aerobic exercise on autonomic and cardiovascular parameters of physically active METHODOLOGY This is a prospective randomized placebo-controlled double-blind crossover trial 40 physically active volunteers will participate in the study They will be qualified for the voluntary study of the male gender who are aged between 18 and 30 years old and have a Body Mass Index BMI between 185 kg m² and 299 kg m² Do not use any medication that may interfere with cardiac autonomic modulation and do not have skeletal muscle damage They will be considered as exclusion criteria for clinical patients as well as those who have already used anabolic steroids or who have cardiorespiratory neurological disorders and other known impairments that prevent the subject from performing the procedures EXPECTED RESULTS Speculated that the protective effects of flavonoids and their antioxidant properties found in Citrus aurantium L optimize autonomic recovery after aerobic exercise In addition HRV can be used to ascertain its SNA activation effects and validate the safety of the applicability of this supplement for overweight populations considering that it is used for this purpose
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None