Ignite Creation Date:
2024-05-06 @ 4:06 PM
Last Modification Date:
2024-10-26 @ 2:03 PM
Study NCT ID:
NCT04873128
Status:
RECRUITING
Last Update Posted:
2023-11-29
First Post:
2021-04-30
Brief Title:
Comparative Genetic and Immune Response Analysis of Different COVID-19 Vaccine Candidates Using Multi-OMICS Approach
Sponsor:
University Hospital Tuebingen
Organization:
University Hospital Tuebingen
Study Overview
Official Title:
Comparative Genetic and Immune Response Analysis of Different COVID-19 Vaccine Candidates Using Multi-OMICS Approach
Status:
RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COVID 19-VAC
Brief Summary:
Reaction of the immune system and the body to a Coronavirus-19 COVID-19 vaccination is so different and ultimately unpredictable has not yet been clarified It is also not yet known why people who have been vaccinated react to a vaccination with sometimes serious side effects Using high-throughput dissecting analytical methods with the suffix OMICS Multi-OMICS methods collective characterization and quantification of pools of biological molecules used in this study on the basis of blood tests data from several molecular levels can be recorded and a holistic picture can be created from this which can depict the connections between these levels
Detailed Description:
Various vaccines against COVID-19 CORONA have now been approved in Germany How and why the reaction of the immune system and the body to a COVID-19 vaccination is so different and ultimately unpredictable has not yet been clarified It is also not yet known why people who have been vaccinated react to a vaccination with sometimes serious side effects There are now initial indications that genetic prerequisites can play a role in the development of the immune response Furthermore we want to examine the long-term protection against Severe Acute Respiratory Syndrome Coronavirus Type 2 SARS-CoV-2 infection through vaccination and learn to understand it better
Using high-throughput dissecting analytical methods with the suffix OMICS Multi-OMICS method used in this study on the basis of blood tests data from several molecular levels can be recorded and a holistic picture can be created from this which can depict the connections between these levels
The expected results can help to gain a better understanding of the underlying reactions to a COVID-19 vaccination and the functioning of the body pathophysiology in the future which could enable the basis for the development of causal therapeutic approaches and improved vaccines
Using high-throughput dissecting analytical methods with the suffix OMICS Multi-OMICS method used in this study on the basis of blood tests data from several molecular levels can be recorded and a holistic picture can be created from this which can depict the connections between these levels
The expected results can help to gain a better understanding of the underlying reactions to a COVID-19 vaccination and the functioning of the body pathophysiology in the future which could enable the basis for the development of causal therapeutic approaches and improved vaccines
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None