Ignite Creation Date:
2024-05-06 @ 4:06 PM
Last Modification Date:
2024-10-26 @ 2:03 PM
Study NCT ID:
NCT04870684
Status:
UNKNOWN
Last Update Posted:
2021-05-03
First Post:
2021-04-09
Brief Title:
Thromboelastometry and Ischemic Stroke ThromboPredict
Sponsor:
University Hospital Caen
Organization:
University Hospital Caen
Study Overview
Official Title:
Interest of Thromboelastometry as a Biomarker of Post-thrombolysis or Post-thrombectemia Revascularization Success in Ischemic Stroke a Prospective Single-center Observational Study in an Emergency Department
Status:
UNKNOWN
Status Verified Date:
2021-04
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In ischemic stroke the recanalization rate after intravenous thrombolysis has been estimated to be less than 50 in patients with proximal intracranial artery occlusion this rate is greater than 80 after endovascular thrombectomy Thromboelastometry is a method of analysis of coagulation and fibrinolysis in whole blood The main objective of this study is to evaluate whether the parameters obtained by thromboelastometry are predictive of revascularization at arteriography during mechanical thrombectomy after treatment with rt-PA thrombolysis
Detailed Description:
This is a single-center prospective observational study at the University Hospital of Caen Any patient presenting a neurological deficit of sudden onset compatible with a ischemic stroke diagnosed on brain imaging and eligible for thrombolysis by rtPA andor a endovascular thrombectomy procedure will be included Clot formation kinetics will be assessed by thromboelastometry ROTEM andor QUANTRA to determine the predictive parameters of revascularization The parameters of clot formation and lysis as well as revascularization according to thrombo-inflammation processes will be studied
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None