Ignite Creation Date:
2024-05-06 @ 4:05 PM
Last Modification Date:
2024-10-26 @ 2:03 PM
Study NCT ID:
NCT04865484
Status:
UNKNOWN
Last Update Posted:
2021-04-29
First Post:
2021-04-27
Brief Title:
Prospective Randomized Comparative Study of the Treatment of Multisegmental Fibrostenosing Crohns Disease
Sponsor:
Sixth Affiliated Hospital Sun Yat-sen University
Organization:
Sixth Affiliated Hospital Sun Yat-sen University
Study Overview
Official Title:
Prospective Randomized Comparative Study of the Treatment of Multisegmental Fibrostenosing Crohns Disease Surgical Resection Plus Endoscopic Stricturotomy Versus Surgical Resection Plus Strictureplasty
Status:
UNKNOWN
Status Verified Date:
2021-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SUREST
Brief Summary:
Stenosis is one of the most frequent complications in patients with Crohns disease CD In particular CD patients with multi segmental intestinal strictures are often faced with short bowel syndrome after repeated or extensive surgical resection
Strictureplasty conserves bowel and minimizes the risk of developing short-bowel syndrome in the short-term and probably long-term Strictureplasty has become an established surgical option in the management of obstructive Crohns disease especially for multiple short fibrous strictures It is particularly suitable for patients at risk for short-bowel syndrome
Endoscopic management shows good efficacy and safety in the treatment of strictures in CD patients The ECCO guideline recommended that endoscopic balloon dilatation is suitable to treat short 5 cm strictures of the terminal ileum in CD Recently Lan et al reported that endoscopic stricturotomy appeared to be more effective in treating CD patients with anastomotic stricture than endoscopic balloon dilatation
However there is no scientific evidence for determining the most appropriate treatment for multiple fibrosis stenosis We designed a prospective randomized comparative study of the treatment of multisegmental fibrostenosing Crohns disease surgical resection plus endoscopic stricturotomy versus surgical resection plus strictureplasty
Strictureplasty conserves bowel and minimizes the risk of developing short-bowel syndrome in the short-term and probably long-term Strictureplasty has become an established surgical option in the management of obstructive Crohns disease especially for multiple short fibrous strictures It is particularly suitable for patients at risk for short-bowel syndrome
Endoscopic management shows good efficacy and safety in the treatment of strictures in CD patients The ECCO guideline recommended that endoscopic balloon dilatation is suitable to treat short 5 cm strictures of the terminal ileum in CD Recently Lan et al reported that endoscopic stricturotomy appeared to be more effective in treating CD patients with anastomotic stricture than endoscopic balloon dilatation
However there is no scientific evidence for determining the most appropriate treatment for multiple fibrosis stenosis We designed a prospective randomized comparative study of the treatment of multisegmental fibrostenosing Crohns disease surgical resection plus endoscopic stricturotomy versus surgical resection plus strictureplasty
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None