Ignite Creation Date:
2024-05-05 @ 5:22 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00445029
Status:
UNKNOWN
Last Update Posted:
2007-10-04
First Post:
2007-03-07
Brief Title:
Pathophysiological Study of Allergic Contact Dermatitis to Para-Phenylenediamine PPD Analysis of Cellular and Molecular Targets in Skin Inflammation
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Pathophysiological Study of Allergic Contact Dermatitis to Para-Phenylenediamine PPD Analysis of Cellular and Molecular Targets in Skin Inflammation
Status:
UNKNOWN
Status Verified Date:
2007-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The current knowledge of the pathophysiology of allergic contact dermatitis is based on the murine model In this model CD8 T cells are effector cells and CD4 T cells regulate the response by limiting the expansion of CD8 T cells The goal of this study is to characterize the pathophysiology of contact dermatitis with patients allergic to para-phenylenediamine PPD
We suppose that the CD8 T cells are the effectors of the allergic contact dermatitis although the regulator cells belong to the LT CD4 population We will test our hypothesis on blood samples and cutaneous biopsies of patients allergic to PPD
We suppose that the CD8 T cells are the effectors of the allergic contact dermatitis although the regulator cells belong to the LT CD4 population We will test our hypothesis on blood samples and cutaneous biopsies of patients allergic to PPD
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None