Ignite Creation Date:
2024-05-06 @ 4:02 PM
Last Modification Date:
2024-10-26 @ 2:03 PM
Study NCT ID:
NCT04858087
Status:
COMPLETED
Last Update Posted:
2021-04-26
First Post:
2021-04-14
Brief Title:
Malawi International Center of Excellence in Malaria Research School-based Cohort
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Epidemiology of Malaria in Malawi Human Hosts and Parasites in Three Districts Part 2 Cross-sectional Surveillance School-based Cohorts
Status:
COMPLETED
Status Verified Date:
2021-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A school-based prospective cohort study was conducted to evaluate the epidemiology of P falciparum Pf infections in school-age children and determine the impact of the screen-and-treat approach on Pf infection and anemia prevalence among students in two different transmission settings Investigators aimed to evaluate how frequently malaria rapid diagnostic tests mRDTs fail to detect low-parasite-density infections as well as whether low-density infections contribute to the burden and health consequences of Pf infection in school-age children and whether they contain gametocytes the parasite stage required for transmission from humans to mosquitos
Detailed Description:
Students were enrolled in four schools in southern Malawi in the rainy March-May and dry season Sept-Nov of 2015 15 students per grade-level grades 1-8 were invited to participate Following enrollment students were evaluated at baseline for screening-and-treatment and followed-up 1 2 and 6 weeks later At each follow-up visit a blood sample was obtained for microscopy and molecular detection of parasites and students were interviewed about bed net use the night prior current or recent illness and use of antimalarial treatment At the final visit a mRDT and hemoglobin test were repeated and parents were interviewed and portable medical records health passports were reviewed to identify intercurrent fever or malaria treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| U19AI089683 | NIH | None | httpsreporternihgovquickSearchU19AI089683 |