Ignite Creation Date:
2024-05-06 @ 4:01 PM
Last Modification Date:
2024-10-26 @ 2:02 PM
Study NCT ID:
NCT04844359
Status:
RECRUITING
Last Update Posted:
2024-03-20
First Post:
2021-03-30
Brief Title:
A Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis
Sponsor:
National Jewish Health
Organization:
National Jewish Health
Study Overview
Official Title:
Development and Validation of a Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PREDICT-HP
Brief Summary:
Up to 135 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression
Detailed Description:
Hypersensitivity pneumonitis is an immunologically mediated form of lung disease resulting from inhalation exposure to a large variety of antigens For unknown reasons a subgroup of patients with HP without a known inciting antigen exposure develops chronic disease with progressive pulmonary fibrosis the leading cause of death Accurately identifying patients at risk of disease progression is necessary for prognosis and therapy
Enrolled subjects will be followed for 24 months and complete 5 visits to one of the study centers Blood biomarkers will be collected in addition to other clinical data to determine if these biomarkers can predict disease progression
Enrolled subjects will be followed for 24 months and complete 5 visits to one of the study centers Blood biomarkers will be collected in addition to other clinical data to determine if these biomarkers can predict disease progression
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None