Ignite Creation Date:
2024-05-06 @ 4:00 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04837638
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-03-13
First Post:
2021-04-06
Brief Title:
Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia
Sponsor:
Laval University
Organization:
Laval University
Study Overview
Official Title:
Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FH-CAC
Brief Summary:
The overarching objective is to evaluate the relationship between diet and coronary artery calcification in patients with heterozygous familial hypercholesterolemia HeFH We will recruit adults with HeFH They will have to complete questionnaires on diet medication and lifestyle Coronary artery calcification will be measured in each patient using a CT scan Physiological and biochemical data will be collected
Detailed Description:
The proposed research will deploy as cross-sectional study including treated adults with genetically-defined HeFH Once recruited participants will be asked to complete web-based questionnaires on diet medication and lifestyle They will thereafter complete a clinical assessment at the Clinical Investigation Unit of the NUTRISS-INAF Research Centre Study staff will measure participants height weight and waist circumference Participants blood pressure will be measured using an automatic blood pressure monitor BP Thru Omron after sitting quietly for 10 minutes Three sequential readings will be taken with three minutes between readings Fasting blood samples 10 mL will be collected from an antecubital vein Body composition will be assessed with dual-energy X-ray absorptiometry DEXA Finally participants will be asked to provide the full list of medication they are using including type dose and duration of use Later on the same day participants will undergo the non-contrast CT scan at the Quebec Heart and Lung Institute Multidetector CT scans without contrast will be performed using a 256 slices helical scanner Brilliance iCT Philips
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None