Ignite Creation Date:
2024-05-06 @ 4:00 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04836078
Status:
COMPLETED
Last Update Posted:
2021-04-08
First Post:
2021-03-25
Brief Title:
Role of Simvastatin Microsponges in Treatment of Periodontitis
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Performance of Simvastatin Microsponges as a Local Treatment for Chronic Periodontitis - Randomized Clinical Trial
Status:
COMPLETED
Status Verified Date:
2021-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
the aim of our study is to enhance the dissolution and subsequently the local penetration of the drug through the sulcus in addition to controlling the drug release so that the drug could be potentially absorbed
Detailed Description:
Patients will be divided randomly into three groups Group Iwill be treated with subgingival debridement and subgengival injection of chitosan 2 gel containing a microsponges formulated SV Group II will be treated with subgingival debridement and subgingival injection of chitosan 2 gel containing free SV and Group III will be treated by subgingival debridement and placebo gel injected subgingivally Pocket depth and clinical attachment loss bone gain were recorded preoperative and six months postoperative for all groups
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None