Ignite Creation Date:
2024-05-06 @ 4:00 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04837079
Status:
UNKNOWN
Last Update Posted:
2021-04-08
First Post:
2021-04-05
Brief Title:
National Survey of Essential Tremor Plus in China
Sponsor:
Xiangya Hospital of Central South University
Organization:
Xiangya Hospital of Central South University
Study Overview
Official Title:
National Survey of Essential Tremor Plus in China
Status:
UNKNOWN
Status Verified Date:
2021-04
Last Known Status:
ENROLLING_BY_INVITATION
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
National Survey of Essential Tremor Plus in ChinaNSETP-Chinais a multicenter cross-sectional study designed to investigate the clinical features of ET-plus in mainland China
Detailed Description:
Essential tremor ET is one of the most common adult-onset movement disorders affecting 09 of the population across all ages worldwide ET is a chronic progressive neurologic disease whose the most recognizable clinical feature is a 412 Hz kinetic tremor of the upper limbs usually occurring during a variety of voluntary movements The etiology and pathogenesis of ET remain elusive
Essential tremor-plus ET-plus is a new term coined in 2018 MDS consensus statement on tremor ET-plus is defined as tremor with the characteristics of essential tremor with additional neurological signs of uncertain clinical significance such as impaired tandem gait questionable dystonic posturing memory impairment or other mild neurological signs of unknown clinical significance that do not suffice to make an additional syndrome classification or diagnosis
ET-plus is a controversial new concept We will use scales or questionnaires to investigate the common soft neurological signs of ET-plus in mainland China The details are as follows 1 The tremors impact on activities of daily living and clinical measurement of ET severity are evaluated by The Essential Tremor Rating Assessment Scale TETRAS 2 Cognitive condition is assessed by Mini Mental State Examination MMSE and Montreal Cognitive Assessment MOCA 3 The non-motor symptoms are evaluated by Non-motor Symptom Scale NMSS 4 Clinical assessment of balance and gait in ET-plus we will use Tandem walk Berg balance scale BBS and 10 meter walk timing test 5 The Unified Dystonia Rating Scale UDRS for evaluation of dystonia in ET-plus 6 The scale for the Assessment and Rating of Ataxia SARA is used to evaluate ataxia in ET-plus
Essential tremor-plus ET-plus is a new term coined in 2018 MDS consensus statement on tremor ET-plus is defined as tremor with the characteristics of essential tremor with additional neurological signs of uncertain clinical significance such as impaired tandem gait questionable dystonic posturing memory impairment or other mild neurological signs of unknown clinical significance that do not suffice to make an additional syndrome classification or diagnosis
ET-plus is a controversial new concept We will use scales or questionnaires to investigate the common soft neurological signs of ET-plus in mainland China The details are as follows 1 The tremors impact on activities of daily living and clinical measurement of ET severity are evaluated by The Essential Tremor Rating Assessment Scale TETRAS 2 Cognitive condition is assessed by Mini Mental State Examination MMSE and Montreal Cognitive Assessment MOCA 3 The non-motor symptoms are evaluated by Non-motor Symptom Scale NMSS 4 Clinical assessment of balance and gait in ET-plus we will use Tandem walk Berg balance scale BBS and 10 meter walk timing test 5 The Unified Dystonia Rating Scale UDRS for evaluation of dystonia in ET-plus 6 The scale for the Assessment and Rating of Ataxia SARA is used to evaluate ataxia in ET-plus
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None