Ignite Creation Date:
2024-05-06 @ 4:00 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04832412
Status:
COMPLETED
Last Update Posted:
2023-06-15
First Post:
2021-04-02
Brief Title:
Effect of BrainPhyt a Microalgae Based Ingredient on Cognitive Function in Healthy Older Subjects
Sponsor:
Microphyt
Organization:
Microphyt
Study Overview
Official Title:
A Randomised Double-blind Placebo-controlled Parallel Study of the Effect of BrainPhyt on Cognitive Function in Healthy Older Subjects
Status:
COMPLETED
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PHAEOSOL-THREE
Brief Summary:
In developed countries the acceleration of the general population ageing has been widely described for decades involving changes in public health policies Among the health issues arising from this demographic change the maintenance of cognitive function will be a major challenge in the next years both in societal and economic terms In this regard some pharmacological and behavioural eg physical activity social involvement intellectually demanding activities preventive approaches have been evaluated to improve cognitive function with ageing Among them dietary interventions showed a potential interest to prevent cognitive decline during ageing In this sense there is a growing interest to find ecological solutions and to meet major societal challenge the use of microalgae as molecule of interest sources is a recent promising approach Marine environments harbour a huge biological diversity of microalgae that represents a large source of almost untapped bioactive compounds This biodiversity comprises 200000 to 2 million species with about 35000 which are described and 15000 maintained in culture collections Microalgae are able to produce bioactive molecules such as pigments fatty acids peptides and sterols Some of these compounds are unique and specifically found in the marine environment and they could be increasingly used as natural bioactive products for targeted applications Fucoxanthin is one of the major carotenoid found in microalgae well known for its neuroprotective effect but to our knowledge no human studies were realized
Thus the objective is to evaluate in healthy older adults the effect of a 24-week period of daily supplementation of high and low BrainPhyt doses on cognitive function parameters Spatial Working Memory scores Attention and vigilance episodic memory executive function stress mood sleep quality and biomarkers
Thus the objective is to evaluate in healthy older adults the effect of a 24-week period of daily supplementation of high and low BrainPhyt doses on cognitive function parameters Spatial Working Memory scores Attention and vigilance episodic memory executive function stress mood sleep quality and biomarkers
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None