Ignite Creation Date:
2024-05-06 @ 4:00 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04837313
Status:
RECRUITING
Last Update Posted:
2021-08-03
First Post:
2020-12-20
Brief Title:
Efficacy and Safety of Fecal Microbiota Transplantation in the Treatment of Parkinsons Disease With Constipation
Sponsor:
Guangzhou First Peoples Hospital
Organization:
Guangzhou First Peoples Hospital
Study Overview
Official Title:
Efficacy and Safety of Fecal Microbiota Transplantation in the Treatment of Parkinsons Disease With Constipation
Status:
RECRUITING
Status Verified Date:
2020-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Parkinsons diseasePD may cause the autonomic nervous systems improper functioning which is responsible for regulating the intestinal tract movement A certain degree of degeneration of digestive system function can cause PD patients to constipation symptoms Studies have shown that up to 63 percent of people with Parkinsons disease experience constipation What is more medications for PD including levodopa and dopamine agonist can also cause constipation In recent years an increasing number of studies have been conducted to investigate gut microflora and their influence on the central nervous system Furthermore some studies of Parkinsons disease have confirmed that gut microflora plays a vital role in the occurrence and development of Parkinsons disease
The purpose of this study is to evaluate the efficacy and safety of fecal microbiota transplantation in the treatment of constipation symptoms in patients with Parkinsons disease receiving a steady dose of levodopa We will also analyze intestinal flora diversity in patients with Parkinsons disease with constipation The investigation of the gut microbiome may emerge as a new therapeutic measure to treat constipation associate with Parkinsons disease
The purpose of this study is to evaluate the efficacy and safety of fecal microbiota transplantation in the treatment of constipation symptoms in patients with Parkinsons disease receiving a steady dose of levodopa We will also analyze intestinal flora diversity in patients with Parkinsons disease with constipation The investigation of the gut microbiome may emerge as a new therapeutic measure to treat constipation associate with Parkinsons disease
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None