Ignite Creation Date:
2024-05-06 @ 3:59 PM
Last Modification Date:
2024-10-26 @ 2:01 PM
Study NCT ID:
NCT04837339
Status:
RECRUITING
Last Update Posted:
2022-08-03
First Post:
2020-11-02
Brief Title:
Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation
Sponsor:
Hopital Foch
Organization:
Hopital Foch
Study Overview
Official Title:
Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation
Status:
RECRUITING
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DATACOL
Brief Summary:
Transplant results vary considerably from one organ to another Lung transplantation has poorer long-term outcomes than other solid organ transplants with a current median post-transplant survival of 60 years Allograft rejection remains the leading cause of morbidity and mortality in all organ groups and is the leading cause of death accounting for more than 40 of deaths beyond the first year after lung transplantation
Each dysfunctions impacts the fate of the graft and therefore the survival of the recipient Their early and precise diagnosis is therefore a major issue The identification of the pathophysiological mechanisms underlying these different subtypes of dysfunction transcriptomics polymorphism of target genes of the immune system or tissue repair cell phenotyping is an essential step It can only be done on the basis of a collection of samples linked to a clinical database allowing to contextualize each sample
Each dysfunctions impacts the fate of the graft and therefore the survival of the recipient Their early and precise diagnosis is therefore a major issue The identification of the pathophysiological mechanisms underlying these different subtypes of dysfunction transcriptomics polymorphism of target genes of the immune system or tissue repair cell phenotyping is an essential step It can only be done on the basis of a collection of samples linked to a clinical database allowing to contextualize each sample
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None