Ignite Creation Date:
2024-05-05 @ 5:21 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00434460
Status:
COMPLETED
Last Update Posted:
2010-09-01
First Post:
2007-02-12
Brief Title:
Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia
Sponsor:
Canadian Critical Care Trials Group
Organization:
Canadian Critical Care Trials Group
Study Overview
Official Title:
Active Observational Study of the Adoption and Transfer of Clinical Practice Guidelines Through Education for Ventilator Associated Pneumonia ABATE VAP Study
Status:
COMPLETED
Status Verified Date:
2010-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ABATEVAP
Brief Summary:
The purpose of this prospective multicentre time-series study is to develop implement refine and evaluate a sustainable behaviour change strategy in the intensive care unit ICU
Detailed Description:
Background
In order to improve the care of our patients it is necessary for research evidence to be translated into clinical practice There are gaps in our understanding of knowledge translation KT and this is evident in the Intensive Care Unit ICU specifically as it applies to the prevention diagnosis and treatment of ventilator-associated pneumonia VAP VAP is associated with a high burden of illness in the critically ill and there is an extensive amount of research evidence on this disease It has been demonstrated that best practice as defined by research evidence is not uniformly applied to VAP In addition recent advances in VAP knowledge need be disseminated and implemented in order to improve patient safety and outcomes from VAP A systematic process of knowledge transfer is crucial to translate this research into evidence-based bedside practice and the development and implementation of evidence based Clinical Practice Guidelines CPGs may facilitate VAP knowledge uptake In addition there is a need to study knowledge translation KT in the ICU since there is little information about optimal KT and CPG implementation strategies in this environment and efforts that are effective in other clinical areas may not result in meaningful change in the ICU
Research Question
What is the effect of VAP CPGs implemented by a multidisciplinary behaviour change strategy consisting of multifaceted educational strategies led by local opinion leaders and augmented with reminders on VAP guideline concordance and on clinical VAP outcomes in the ICU
Research Plan
Data will only be collected on consecutive patients mechanically ventilated for at least 48 hours The following health care professionals will be studied to assess the behaviour change strategy for the VAP CPGs physicians intensivists ICU fellows ICU rotating residents nurses respiratory therapists dieticians physiotherapists and ICU administrators
The study will be conducted in 3 phases
1 Development of a behaviour change strategy consisting of three components
Local opinion leader team
Educational strategy
Reminder system
2 Prospective implementation of the behaviour change strategy over a 24 month period
3 Prospective evaluation of the behaviour change strategy over a 24 month period
Concordance with VAP guidelines over time
Factors associated with VAP guideline concordance
Clinical VAP outcomes pre- and post-guideline implementation
In order to improve the care of our patients it is necessary for research evidence to be translated into clinical practice There are gaps in our understanding of knowledge translation KT and this is evident in the Intensive Care Unit ICU specifically as it applies to the prevention diagnosis and treatment of ventilator-associated pneumonia VAP VAP is associated with a high burden of illness in the critically ill and there is an extensive amount of research evidence on this disease It has been demonstrated that best practice as defined by research evidence is not uniformly applied to VAP In addition recent advances in VAP knowledge need be disseminated and implemented in order to improve patient safety and outcomes from VAP A systematic process of knowledge transfer is crucial to translate this research into evidence-based bedside practice and the development and implementation of evidence based Clinical Practice Guidelines CPGs may facilitate VAP knowledge uptake In addition there is a need to study knowledge translation KT in the ICU since there is little information about optimal KT and CPG implementation strategies in this environment and efforts that are effective in other clinical areas may not result in meaningful change in the ICU
Research Question
What is the effect of VAP CPGs implemented by a multidisciplinary behaviour change strategy consisting of multifaceted educational strategies led by local opinion leaders and augmented with reminders on VAP guideline concordance and on clinical VAP outcomes in the ICU
Research Plan
Data will only be collected on consecutive patients mechanically ventilated for at least 48 hours The following health care professionals will be studied to assess the behaviour change strategy for the VAP CPGs physicians intensivists ICU fellows ICU rotating residents nurses respiratory therapists dieticians physiotherapists and ICU administrators
The study will be conducted in 3 phases
1 Development of a behaviour change strategy consisting of three components
Local opinion leader team
Educational strategy
Reminder system
2 Prospective implementation of the behaviour change strategy over a 24 month period
3 Prospective evaluation of the behaviour change strategy over a 24 month period
Concordance with VAP guidelines over time
Factors associated with VAP guideline concordance
Clinical VAP outcomes pre- and post-guideline implementation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None