Ignite Creation Date:
2024-05-05 @ 5:20 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00436488
Status:
COMPLETED
Last Update Posted:
2007-02-19
First Post:
2007-02-16
Brief Title:
Frequency of ICAM-1 Polymorphisms in Obese Subjects
Sponsor:
Istituto Auxologico Italiano
Organization:
Istituto Auxologico Italiano
Study Overview
Official Title:
Study of the Association Between ICAM-1 Polymorphisms and Severe Obesity
Status:
COMPLETED
Status Verified Date:
2007-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The genetic contribution to the development of obesity is now well recognized However obesity is a polygenic disease and thus many genes are likely to be involved This study aims to investigate the possible association between specific variants of the gene coding for the Intercellular Adhesion Molecule-1 ICAM-1and the development of severe obesity in an Italian population
Detailed Description:
Severely obese subjects referred to our institution will be evaluated For the aim of the study a venous blood sample will be obtained from these subjects and from a group of normal weight volunteers Genomic DNA will be extracted from the blood samples and analysed by standard molecular biology techniquesThe allelic and genotype frequencies of the two ICAM-1 variants will be calculated in the obese and control groups The statistical significance of possible differences will be determined
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None