Ignite Creation Date:
2024-05-06 @ 3:55 PM
Last Modification Date:
2024-10-26 @ 1:59 PM
Study NCT ID:
NCT04804358
Status:
UNKNOWN
Last Update Posted:
2022-01-04
First Post:
2021-03-10
Brief Title:
Study of the Difference Between Anorexia Nervosa With a History of Psychological Trauma and Classical Anorexia Nervosa on the Neurocognitive and Neurophysiological Factors
Sponsor:
University Hospital Montpellier
Organization:
University Hospital Montpellier
Study Overview
Official Title:
Study of the Difference Between Anorexia Nervosa With a History s of Psychological Trauma AM-T and Classical Anorexia Nervosa AM-C on the Neurocognitive and Neurophysiological Factors
Status:
UNKNOWN
Status Verified Date:
2021-12
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ATAC
Brief Summary:
Recent studies suggest that patients with an history of trauma may represent a specific subtype of anorexia nervosa AM underlined by specific neurobiological and psychopathological mechanisms Thus AM-T subjects would manifest cognitive specific difficulties in executive functions emotional emotional disruption impulsivity etc and neurobiological secretion of kynurenine and neurokinins in the face of stress caracteristics different from those of AM subjects
Detailed Description:
We will recruit a total of 100 patients with a diagnosis of anorexia nervosa in the university hospital of Montpellier 50 patients with an history of psychological trauma and 50 patients without any history of psychological trauma
Participation consists of a half-day visit Patients will perform clinical and neuropsychological assessments and an exposition test During this test participants will be exposed for 7 minutes to neutral positive or negative emotional photos Heart rate variability will be determined through a Biopac MP160 before during and after this event Saliva samples to measure kynurenin tryptophan substance P and neurokinin-1 will be collected before and directly after the test
Participation consists of a half-day visit Patients will perform clinical and neuropsychological assessments and an exposition test During this test participants will be exposed for 7 minutes to neutral positive or negative emotional photos Heart rate variability will be determined through a Biopac MP160 before during and after this event Saliva samples to measure kynurenin tryptophan substance P and neurokinin-1 will be collected before and directly after the test
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None