Ignite Creation Date:
2024-05-06 @ 3:55 PM
Last Modification Date:
2024-10-26 @ 1:59 PM
Study NCT ID:
NCT04804449
Status:
COMPLETED
Last Update Posted:
2023-01-26
First Post:
2021-03-08
Brief Title:
Prospective Longitudinal Effects of Intra-articular Corticosteroid Injection on Synovial Fluid Oxygen
Sponsor:
University of Oxford
Organization:
University of Oxford
Study Overview
Official Title:
Prospective Longitudinal Effects of Intra-articular Corticosteroid Injection on Synovial Fluid Oxygen
Status:
COMPLETED
Status Verified Date:
2022-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
POLO
Brief Summary:
Inflammatory arthritis such as rheumatoid arthritis RA and psoriatic arthritis PsA are characterized by synovial inflammation of joints potentially leading to joint destruction and functional disability Inflamed joints have lower oxygen levels Studying how oxygen level within the joint affect inflammation may lead to new treatments for patients with arthritis Anti-inflammatory corticosteroid injection into the joint is well tolerated and widely used in clinical practice but its effects on oxygen level within joints is unknown Therefore patients who require corticosteroid injection into the joint as routine clinical care will have biological samples collected before and after the injection This will give new information to put into context the biological effects within the joint and accelerate development of new treatment approaches in the future
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None