Ignite Creation Date:
2024-05-06 @ 3:53 PM
Last Modification Date:
2024-10-26 @ 1:59 PM
Study NCT ID:
NCT04797819
Status:
COMPLETED
Last Update Posted:
2021-03-24
First Post:
2021-03-12
Brief Title:
Serum Soluble ST2 and Plaque Vulnerability in Patients With Acute Coronary Syndrome
Sponsor:
RenJi Hospital
Organization:
RenJi Hospital
Study Overview
Official Title:
Elevated Serum Soluble ST2 Level is Associated With Increased Plaque Vulnerability in Patients With Non-ST Elevation Acute Coronary Syndrome
Status:
COMPLETED
Status Verified Date:
2021-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aimed to assess the association between serum sST2 level and plaque vulnerability in ACS patients It is hypothesized that serum sST2 level may be related to plaque components and closely associated with plaque vulnerability
Detailed Description:
Serum soluble suppression of tumorigenicity-2 sST2 has emerged as a novel biomarker of atherosclerotic disease This study aimed to investigate whether elevated serum sST2 level is related to coronary plaque components detected on coronary computed tomography angiography CCTA and plaque vulnerability in non-ST elevation acute coronary syndromes ACS patients 167 lesions in 120 non-ST elevation ACS patients were prospectively enrolled and evaluated by CCTA in this study Blood were taken from antecubital vein during patients hospitalization for angiography Serum sST2 level was measured by commerical ELISA kits Presage ST2 Assay Kit Critical Diagnostics CCTA were performed using a 320-slice CT scanner Aquilion ONE Toshiba Medical Systems Otawara Japan Coronary plaque components were analyzed cross each of the lesions using commercialized software package QAngio CT Medis The Netherlands
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None