Ignite Creation Date:
2024-05-06 @ 3:53 PM
Last Modification Date:
2024-10-26 @ 1:59 PM
Study NCT ID:
NCT04798365
Status:
COMPLETED
Last Update Posted:
2023-03-14
First Post:
2021-03-09
Brief Title:
Antimicrobial Stewardship in UTIs in Nursing Homes
Sponsor:
Medical University of Graz
Organization:
Medical University of Graz
Study Overview
Official Title:
Implementation of an Antimicrobial Stewardship Program Targeting Residents With Urinary Tract Infections in Long-term Care Facilities
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background The widespread inappropriate use of antimicrobial substances drives resistance development at the individual and population level all over the world In long-term care facilities LTCF antibiotics are among the most frequently prescribed medications More than one third of antibiotics prescribed in LTCFs are for urinary tract infections UTI Studies have shown that 30 - 40 of antibiotic courses prescribed in LTCFs were unnecessary and that more than two-thirds were inappropriate based on society guidelines
Preliminary data A surveillance study on healthcare-associated UTIs at LTCFs of the Geriatric Health Centers Graz revealed that guideline recommendations on antimicrobial choice were met in only 50 of patients The most frequently used antimicrobial substances for UTI were quinolones
Aims Using a multifaceted bundle of antimicrobial stewardship interventions consisting of clinical practice guidelines care pathways and local as well as web-based education and training targeting nursing staff as well as physicians we aim to improve the quality of antimicrobial prescriptions for UTIs in four LTCFs in Graz Austria
Design Non-randomized cluster controlled intervention study Setting The Geriatric Health Centers Graz are a local institution comprising among others 4 LTCFs total of 400 beds These will serve as intervention group Four LTCFs located in the surroundings of Graz will serve as control group
Intervention The main components of the intervention are 1 two sessions of voluntary continuing medical education on the urinary tract infection program in each LTCF for physicians and nursing staff 2 distribution of educations materials such as written guidelines on antibiotic prescribing including a smart phone friendly version 3 implementation of the project homepage as a platform to distribute guidelines and educational videos and to enable physicians to ask questions which will be answered by an infectious disease physician
Outcomes The primary outcome will be the proportion of adequate prescriptions adequate in terms of antimicrobial choice Secondary outcomes include proportion of adequate prescriptions adequate in terms of decision to treat number of cases with clinical failure number of admissions to hospital due to UTI number of adverse events attributed to antimicrobial treatment for UTI percentage of extended spectrum betalactamase ESBL producing enterobacteria isolated from urinary cultures
Preliminary data A surveillance study on healthcare-associated UTIs at LTCFs of the Geriatric Health Centers Graz revealed that guideline recommendations on antimicrobial choice were met in only 50 of patients The most frequently used antimicrobial substances for UTI were quinolones
Aims Using a multifaceted bundle of antimicrobial stewardship interventions consisting of clinical practice guidelines care pathways and local as well as web-based education and training targeting nursing staff as well as physicians we aim to improve the quality of antimicrobial prescriptions for UTIs in four LTCFs in Graz Austria
Design Non-randomized cluster controlled intervention study Setting The Geriatric Health Centers Graz are a local institution comprising among others 4 LTCFs total of 400 beds These will serve as intervention group Four LTCFs located in the surroundings of Graz will serve as control group
Intervention The main components of the intervention are 1 two sessions of voluntary continuing medical education on the urinary tract infection program in each LTCF for physicians and nursing staff 2 distribution of educations materials such as written guidelines on antibiotic prescribing including a smart phone friendly version 3 implementation of the project homepage as a platform to distribute guidelines and educational videos and to enable physicians to ask questions which will be answered by an infectious disease physician
Outcomes The primary outcome will be the proportion of adequate prescriptions adequate in terms of antimicrobial choice Secondary outcomes include proportion of adequate prescriptions adequate in terms of decision to treat number of cases with clinical failure number of admissions to hospital due to UTI number of adverse events attributed to antimicrobial treatment for UTI percentage of extended spectrum betalactamase ESBL producing enterobacteria isolated from urinary cultures
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None