Ignite Creation Date:
2024-05-06 @ 3:52 PM
Last Modification Date:
2024-10-26 @ 1:58 PM
Study NCT ID:
NCT04783623
Status:
COMPLETED
Last Update Posted:
2021-03-05
First Post:
2021-03-02
Brief Title:
Cohort Study of Endometriosis at Different Sites
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
Analysis of Clinical Characteristics and Risk Factors of Recurrence of Endometriosis at Different Sites
Status:
COMPLETED
Status Verified Date:
2021-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To present the clinical characteristics of pelvic or extra-pelvic endometriosis and explore the potential risk factors of pathogenesis and recurrence by comparing patients with endometriosis at different sites
Detailed Description:
Endometriosis is a chronic inflammatory disease defined as the presence of endometrial glands and stroma outside of the internal epithelial lining of the cavum uteri affecting up to 10 of reproductive age women It is rarely found in extrapelvic locationsThis form of endometriosis may be difficult to diagnosis due to pleomorphic presentation Despite complete excision with a safe margin and histopathological examination has been considered as definitive diagnosis and primary therapeutic treatment for extra-pelvic endometriosis what is understood mainly comes from case reports and retrospective observations with limited number of cases Moreover approximately 6-14 of patients with PEM who had underwent narrowly operative resection still suffered recurrent lesions while risk factors were barely identified
Patients with endometriosis at different sites in our hospital were collected for analysis of clinical characteristics namely demographic information medical history surgical records pathological and imaging reports serum levels of cancer antigen 125 CA125 peri-operative medication During long-term follow-up prognosis of individuals could be identified by telephone or clinical interview Based on data from medical records or clinical observation risk model predicting recurrence will be established by comparing patients with different outcomes or exposed to different risk factors Thus management of endometriosis might be improved Hopefully pathogenesis of recurrent and primary endometriosis might be explained
Patients with endometriosis at different sites in our hospital were collected for analysis of clinical characteristics namely demographic information medical history surgical records pathological and imaging reports serum levels of cancer antigen 125 CA125 peri-operative medication During long-term follow-up prognosis of individuals could be identified by telephone or clinical interview Based on data from medical records or clinical observation risk model predicting recurrence will be established by comparing patients with different outcomes or exposed to different risk factors Thus management of endometriosis might be improved Hopefully pathogenesis of recurrent and primary endometriosis might be explained
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None