Ignite Creation Date:
2024-05-06 @ 3:51 PM
Last Modification Date:
2024-10-26 @ 1:58 PM
Study NCT ID:
NCT04773574
Status:
NOT_YET_RECRUITING
Last Update Posted:
2021-06-30
First Post:
2021-02-25
Brief Title:
Physiologic Ocular Changes During Pregnancy in Women With High Myopia
Sponsor:
Khon Kaen University
Organization:
Khon Kaen University
Study Overview
Official Title:
Physiologic Ocular Changes During Pregnancy in Women With High Myopia
Status:
NOT_YET_RECRUITING
Status Verified Date:
2021-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The prevalence of myopia is seemingly increasing and it is one of the major causes of blindness High myopia is defined as a refractive error with spherical equivalent exceeding -6 diopters andor the axial length longer than 265 mm The global prevalence of high myopia is estimated to rise from 27 of the world population in 2010 to 98 of the world population in 2050 High myopia is characterized by axial length elongation and consequent stretching of the posterior eye wall thin retina and choroid There are many complications of high myopia such as posterior staphyloma lacquer cracks and myopic choroidal neovascularization Normal labour may cause the ocular complication in pregnant women with high myopia such as macular hemorrhage Therefore the caesarean section with epidural anesthesia is recommended Moreover there is no standard screening guideline for pregnant women with high myopia
Detailed Description:
There are few studies of posterior ocular changes during pregnancy A recent meta-analysis showed that the choroidal thickness and retinal vascular density were increased during pregnancy especially in the 3rd trimester From the literature review there is only one publication of physiologic ocular changes during pregnancy in high myopia Chen et al demonstrated that the choroidal thickness was increased significantly in the 3rd trimester However the changes of retinal vascular density in pregnant women with high myopia have never been studied before
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None