Ignite Creation Date:
2024-05-06 @ 3:50 PM
Last Modification Date:
2024-10-26 @ 1:58 PM
Study NCT ID:
NCT04779359
Status:
UNKNOWN
Last Update Posted:
2021-03-03
First Post:
2021-03-01
Brief Title:
Role of Lymphocyte Subsets and Laboratory Measurements in COVID-19 Disease
Sponsor:
Shanghai Public Health Clinical Center
Organization:
Shanghai Public Health Clinical Center
Study Overview
Official Title:
The Predictive Role of Lymphocyte Subsets and Laboratory Measurements in COVID-19 Disease- A Retrospective Study
Status:
UNKNOWN
Status Verified Date:
2021-03
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To investigate the predictive role of lymphocyte subsets and other laboratory measurements in adult patients with COVID-19This was a single center retrospective study that involved adult patients with confirmed diagnosis of COVID-19 Electronic medical records were reviewed Data including age sex symptom from onset to hospital admission and laboratory findings at admission of hospitalized patients with confirmed COVID-19 were extracted and analyzed retrospectivelyThis study indicates that the levels of lymphocyte subsets CD4 and CD8 are associated with disease progression and severity along with prognosis in patients with COVID-19
Detailed Description:
This was a single center retrospective study that involved adult patients with confirmed diagnosis of COVID-19 Electronic medical records were reviewed Data including age sex symptom from onset to hospital admission and laboratory findings at admission of hospitalized patients with confirmed COVID-19 were extracted and analyzed retrospectively Identifying the possible immune factors and laboratory parameters is requisite for the early identification of patients with severe COVID-19 and timely intervention for control of the disease There is an unmet need to establish robust clinical cutoffs of lymphocyte subsets for predicting risk associated with ICU admission mechanical ventilation and mortality in COVID-19 patients This retrospective study was thus carried out to improve knowledge and clinical utility of lymphocyte subset measurements together with other laboratory measurements and clinical information for understanding prognosis in COVID-19 patients These findings suggest that alterations in lymphocyte subsets and laboratory measurements play a significant role in the progression of COVID-19
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None