Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:01 AM
Study NCT ID:
NCT00000291
Status:
COMPLETED
Last Update Posted:
2017-01-12
First Post:
1999-09-20
Brief Title:
Effects of Labetalol on Human Cocaine Use - 8
Sponsor:
National Institute on Drug Abuse NIDA
Organization:
National Institute on Drug Abuse NIDA
Study Overview
Official Title:
Effects of Labetalol on Human Cocaine Use
Status:
COMPLETED
Status Verified Date:
2016-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine the effect of labetalol treatment on the subjective and physiological effects of cocaine
Detailed Description:
The goal of this study was to investigate the safety and utility of labetalol an alpha and beta adrenergic block for cocaine dependence in humans A total of 12 subjects were enrolled in this double blind placebo controlled outpatient study After baseline measures are obtained three experimental sessions were held at least 2 days apart Subjects were administered a single low 100 mg or high dose of labetalol 200mg or placebo on each of 3 experimental sessions The labetalol doses were given in ascending order and the placebo treatment were randomly inserted into the sequence A single dose of smoked cocaine 04 mgkg was administered 2 hrs after labetalol or placebo treatment During the sessions several subjective behavioral and physiological measures were obtained
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| P50-09259-8 | None | None | None |