Ignite Creation Date:
2024-05-06 @ 3:48 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04763434
Status:
UNKNOWN
Last Update Posted:
2021-02-21
First Post:
2021-02-17
Brief Title:
Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy A Prospective Randomized Triple-blind Study
Sponsor:
Gansu Provincial Hospital
Organization:
Gansu Provincial Hospital
Study Overview
Official Title:
Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy A Prospective Randomized Triple-blind Study
Status:
UNKNOWN
Status Verified Date:
2021-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The hypothesis is whether perineural dexamethasone and dexmedetomidine prolonged the duration of analgesia as compared with either perineural dexamethasone or perineural dexmedetomidine after TPVB
Detailed Description:
Design A prospective randomized controlled study Setting Single-center university hospital Participants The study included 90 patients undergoing lobectomy under general anesthesia
Interventions The patients were allocated randomly into the following 3 groups 20 ml mixture of 375 mg ropivacaine with 5 mg dexamethasone RS group or 1 µgkg dexmedetomidine RM group or with 1 µgkg dexmedetomidine and 5 mg dexamethasone RSM group Ultrasound-guided TPVB was performed at 4 points-T4-5 T5-6 T6-7 and T7-8 of the surgical side 5 mL of solution were injected at each point Postoperatively the PCIA was used as part of multimodal analgesia and all patients recieve
Interventions The patients were allocated randomly into the following 3 groups 20 ml mixture of 375 mg ropivacaine with 5 mg dexamethasone RS group or 1 µgkg dexmedetomidine RM group or with 1 µgkg dexmedetomidine and 5 mg dexamethasone RSM group Ultrasound-guided TPVB was performed at 4 points-T4-5 T5-6 T6-7 and T7-8 of the surgical side 5 mL of solution were injected at each point Postoperatively the PCIA was used as part of multimodal analgesia and all patients recieve
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None