Ignite Creation Date:
2024-05-06 @ 3:48 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04767256
Status:
COMPLETED
Last Update Posted:
2022-03-29
First Post:
2021-02-19
Brief Title:
Intravenous Dexamethasone and Dexmedetomidine on the Analgesic Efficacy of Erector Spinae Plane Block
Sponsor:
Huazhong University of Science and Technology
Organization:
Huazhong University of Science and Technology
Study Overview
Official Title:
Intravenous Dexamethasone and Dexmedetomidine on the Analgesic Efficacy of Erector Spinae Plane Block for Posterior Lumbar Interbody Fusion Surgery
Status:
COMPLETED
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients having lumbar spinal fusion often complain about severe postoperative pain and postoperative rehabilitation process can be affected negatively Postoperative pain that cannot be well controlled may lead to delayed mobilization pulmonary and thromboembolic complications prolonged hospital stays and chronic pain syndromes Pain after spinal surgery can arise from several different tissues such as the vertebrae disks ligaments dura facet joint muscle fascia and subcutaneous and cutaneous tissues
Ultrasound-guided lumbar erector spinae plane block ESPB has been shown to reduce postoperative pain in patients undergoing posterior lumbar interbody fusion PLIF However the duration of analgesia after single-shot ESPB with commonly used local anesthetics is reported to be no more than 12 h which often not long enough to provide satisfactory postoperative pain relief as the pain typically lasts for several days Compared with perineural route intravenous additives to local anesthetics are commonly accepted as its safety and efficiency have been reported Moreover co-administration of intravenous dexamethasone and dexmedetomidine significantly prolonged the time to first rescue analgesic request after single-shot interscalene brachial plexus block However more data are needed especially for lumbar ESPB
Ultrasound-guided lumbar erector spinae plane block ESPB has been shown to reduce postoperative pain in patients undergoing posterior lumbar interbody fusion PLIF However the duration of analgesia after single-shot ESPB with commonly used local anesthetics is reported to be no more than 12 h which often not long enough to provide satisfactory postoperative pain relief as the pain typically lasts for several days Compared with perineural route intravenous additives to local anesthetics are commonly accepted as its safety and efficiency have been reported Moreover co-administration of intravenous dexamethasone and dexmedetomidine significantly prolonged the time to first rescue analgesic request after single-shot interscalene brachial plexus block However more data are needed especially for lumbar ESPB
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None