Ignite Creation Date:
2024-05-06 @ 3:48 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04767165
Status:
RECRUITING
Last Update Posted:
2023-03-08
First Post:
2021-02-16
Brief Title:
Quantitative MRI of Bone Marrow in Patients With Acute Lymphoblastic Leukemia
Sponsor:
Federal Research Institute of Pediatric Hematology Oncology and Immunology
Organization:
Federal Research Institute of Pediatric Hematology Oncology and Immunology
Study Overview
Official Title:
Clinical Pilot Study of Quantitative MRI Assessment of Bone Marrow in Patients With Acute Lymphoblastic Leukemia and Patients Without Hematopoietic Disorders From 6 to 18 Years Old
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study is aimed at assessing changes in the bone marrow of patients from 6 to 18 years old with a diagnosis of acute lymphoblastic leukemia during chemotherapy Patients of the same age without hematological diseases will be recruited as a control group
Detailed Description:
The ratio of fat to water in the bone marrow depends on the cellularity of the bone marrow In addition to the waterfat ratio in bone marrow there are also other parameters for quantitative MRI assessment These include the apparent diffusion coefficient ACD the T1 relaxation time mapping of the macromolecular proton fraction The undoubted advantage of MRI is its non-invasiveness and the ability to assess any localization of the bone marrow
MRI may become a new non-invasive method for assessing the ratio of fat to cells in the bone marrow in children with hematological malignancies which can help in making a diagnosis and monitoring the response to therapy
MRI may become a new non-invasive method for assessing the ratio of fat to cells in the bone marrow in children with hematological malignancies which can help in making a diagnosis and monitoring the response to therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None