Ignite Creation Date:
2024-05-06 @ 3:48 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04769635
Status:
COMPLETED
Last Update Posted:
2021-02-24
First Post:
2021-02-20
Brief Title:
CPAP Therapy in Obstructive Sleep Apnea Patients With Pulmonary Hypertension
Sponsor:
Zagazig University
Organization:
Zagazig University
Study Overview
Official Title:
Impact of Continuous Positive Airway Pressure Therapy on Pulmonary Hypertension and Exercise Capacity in Newly Diagnosed Obstructive Sleep Apnea Patients
Status:
COMPLETED
Status Verified Date:
2021-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
All patients are newly diagnosed Obstructive Sleep Apnea patients performing full night polysmnographic sleep study whose echocardiographic findings elucidate presence of pulmonary hypertensionPH These patients seemed to have PH if mPAP 25 mmHg All studied patients were received CPAP therapy with average cumulative adherence 4 hday of 70 nights 380 obtained from device download with AHI5 hr
Echocardiography
It was performed initially to diagnose pulmonary hypertension and repeated after three months of CPAP therapy as a follow up All enrolled patients were subjected to trans-thoracic echocardiography using Ultrasound system Vivid I GE Healthcare Little Chalfont UK with a 25 MHz transducer Certain measurements were then used to calculate mPAP
Patients were considered to have PH if mPAP 25 mmHg and were classified into mild 20-40 mmHg moderate 41-55 mmHg and severe 55 mmHg degrees
Evidence of PH is found by Doppler echocardiography showing an elevated right ventricular systolic pressure RVSP
Echocardiography
It was performed initially to diagnose pulmonary hypertension and repeated after three months of CPAP therapy as a follow up All enrolled patients were subjected to trans-thoracic echocardiography using Ultrasound system Vivid I GE Healthcare Little Chalfont UK with a 25 MHz transducer Certain measurements were then used to calculate mPAP
Patients were considered to have PH if mPAP 25 mmHg and were classified into mild 20-40 mmHg moderate 41-55 mmHg and severe 55 mmHg degrees
Evidence of PH is found by Doppler echocardiography showing an elevated right ventricular systolic pressure RVSP
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None