Ignite Creation Date:
2024-05-06 @ 3:47 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04753008
Status:
UNKNOWN
Last Update Posted:
2021-02-12
First Post:
2021-02-05
Brief Title:
Respiratory Effects of Dopamine in the Perioperative Care
Sponsor:
Szeged University
Organization:
Szeged University
Study Overview
Official Title:
Respiratory Effects of Dopamine in the Perioperative Care
Status:
UNKNOWN
Status Verified Date:
2021-02
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DOPHUMAN
Brief Summary:
Dopamine is frequently used as an inotropic drug to elevate cardiac output In addition to the beneficial cardiac effect of this drug the few previous studies addressing its ability to alter the airway tone reported controversial results
Thus the investigators aimed at clarifying the potential of dopamine to alter gas exchange outcomes and the airway tone in patients undergoing cardiac surgeries with cardiopulmonary bypass
Blood gas parameters airway resistance tissue damping and tissue elastance will be measured in the patients before the CPB immediately after CPB and 5 min after administration of dopamine 3 mcgkgmin
The importance of the research is to reveal whether the beneficial mechanical changes after dopamine administrations are associated with improvements in gas exchange outcomes Clarification of this research question have scientific relevance and may also improves patient outcomes
Thus the investigators aimed at clarifying the potential of dopamine to alter gas exchange outcomes and the airway tone in patients undergoing cardiac surgeries with cardiopulmonary bypass
Blood gas parameters airway resistance tissue damping and tissue elastance will be measured in the patients before the CPB immediately after CPB and 5 min after administration of dopamine 3 mcgkgmin
The importance of the research is to reveal whether the beneficial mechanical changes after dopamine administrations are associated with improvements in gas exchange outcomes Clarification of this research question have scientific relevance and may also improves patient outcomes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None