Ignite Creation Date:
2024-05-06 @ 3:47 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04757129
Status:
RECRUITING
Last Update Posted:
2024-05-13
First Post:
2021-01-29
Brief Title:
Changes of Cardiopulmonary Function After Thrombolysis in Patients With Pulmonary Embolism
Sponsor:
Bin He
Organization:
Nanjing Medical University
Study Overview
Official Title:
Dynamic Changes of Circulatory and Respiratory Function After Thrombolysis in Patients With Acute Pulmonary Embolism
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CCFATAPE
Brief Summary:
The investigators expect to enroll about 80-100 acute pulmonary embolism patients treated with thrombolysis in two hospitals Dynamic changes of cardiopulmonary function after thrombolysis are detected to evaluate which indicators can quickly reflect the effectiveness of thrombolysis
Detailed Description:
About 80-100 acute pulmonary embolismAPE patients treated with thrombolysis are enrolled in the First Affiliated Hospital with Nanjing Medical University and Nanjing Drum Town Hospital from January 1 2020 to June 30 2024 According to the 2019 ESC guideline the standards for thrombolysis in APE patients are as follows within 2 weeks of onset high-risk pulmonary embolism medium-high-risk pulmonary embolism with symptoms of aggravation
Investigators dynamically monitor cardiopulmonary function of participants after thrombolysis including blood pressure heart rate respiratory rate blood gas analysis 2-dimensional echocardiography left and right ventricular diameter pulmonary artery pressure interventricular septum and laboratory tests cTnTpro-BNPparticipants are divided into two groups thrombolytic success group and thrombolytic failure group according the previously reported criterion which is evaluated 48h after thrombolysis
Cardiopulmonary characteristics are analyzed to seek accurate and rapid index to reflect success of thrombolysis
Investigators dynamically monitor cardiopulmonary function of participants after thrombolysis including blood pressure heart rate respiratory rate blood gas analysis 2-dimensional echocardiography left and right ventricular diameter pulmonary artery pressure interventricular septum and laboratory tests cTnTpro-BNPparticipants are divided into two groups thrombolytic success group and thrombolytic failure group according the previously reported criterion which is evaluated 48h after thrombolysis
Cardiopulmonary characteristics are analyzed to seek accurate and rapid index to reflect success of thrombolysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None