Ignite Creation Date:
2024-05-06 @ 3:47 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04757597
Status:
UNKNOWN
Last Update Posted:
2021-06-16
First Post:
2021-02-13
Brief Title:
Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Cerebral Amyloid Angiopathy-related Intracerebral HemorrhageA Multicenter Randomized Controlled Study
Status:
UNKNOWN
Status Verified Date:
2021-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RIC-CAAH
Brief Summary:
Cerebral amyloid angiopathy-related intracerebral CAAH hemorrhage is second factor of primary intracerebral hemorrhage However no effective prevention and treatment strategies have been established Remote ischemic conditioning is a neuroprotective strategy In animal studiesRIC is efficiency in accelerating the absorption of hematoma Therefore the investigators plan to carry out this research to evaluate the safety and efficacy of RIC in patients with CAA related ICH
Detailed Description:
In China primary intracerebral hemorrhage accounts for 80-85 of all types of intracerebral hemorrhage while cerebral amyloid angiopathy-related intracerebral hemorrhage is the second factor accounting for approximately 20-30 It is often characterized by repeated and multifocal lobar hemorrhage which will not only cause neurological deficit on the limbs but also influence the cognitive level of patients and may even be life-threatening At present the role of surgery in CAA-related ICH is controversial and there is no effective prevention and treatment strategies have been established Additionally it is always associated with a low rate of good prognosis11-60 and a high risk of recurrent ICH 10-60 Thus a novel approach which can improve the clinical outcome and reduce the risk of recurrent intracerebral hemorrhage is urgently needed
Remote ischemic conditioning RIC has been developed as a neuroprotective strategy to prevent and treat acute ischemic stroke and small cerebrovascular disease Additionally clinical research testified that RIC is safe and feasible for patients with subarachnoid hemorrhage In animal studies RIC is efficiency in accelerating the absorption of hematoma Therefore the investigators plan to carry out this research to evaluate the safety and efficacy of RIC in patients with CAA related ICH
Remote ischemic conditioning RIC has been developed as a neuroprotective strategy to prevent and treat acute ischemic stroke and small cerebrovascular disease Additionally clinical research testified that RIC is safe and feasible for patients with subarachnoid hemorrhage In animal studies RIC is efficiency in accelerating the absorption of hematoma Therefore the investigators plan to carry out this research to evaluate the safety and efficacy of RIC in patients with CAA related ICH
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None