Ignite Creation Date:
2024-05-06 @ 3:47 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04753996
Status:
RECRUITING
Last Update Posted:
2024-03-15
First Post:
2021-02-09
Brief Title:
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
Sponsor:
Mayo Clinic
Organization:
Mayo Clinic
Study Overview
Official Title:
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this research is to create a collection of bile bile duct brushings and medical information from people with Primary Sclerosing Cholangitis PSC and controls to learn more about changes that occur in the liver
Detailed Description:
The study will ask participants to provide bile andor bile duct cytology brushings at time of endoscopic retrograde cholangiopancreatography ERCP or cholecystectomy gallbladder removal The bile and brushings will be used to generate and perpetuate bile-derived organoids using an established matrigel-based protocol These organoids will then be used in downstream experiments to better understand disease-specific alterations to biological pathways informative of disease pathogenesis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| RC2DK118619 | NIH | None | httpsreporternihgovquickSearchRC2DK118619 |