Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04758637
Status:
COMPLETED
Last Update Posted:
2024-04-11
First Post:
2021-02-12
Brief Title:
AESOPS Trial 2 AESOPS-2 Availability of Opioid Harm
Sponsor:
University of Southern California
Organization:
University of Southern California
Study Overview
Official Title:
Application of Economics Social Psychology to Improve Opioid Prescribing Safety Trial 2 AESOPS-2 Availability of Opioid Harm
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AESOPS-2
Brief Summary:
The opioid epidemic is the largest man-made public health crisis the United States has faced The objective of Trial 2 of the Application of Economics Social psychology to improve Opioid Prescribing Safety AESOPS-2 study is to discourage unnecessary opioid prescribing by increasing the salience of negative patient outcomes associated with opioid use
Detailed Description:
In AESOPS-2 a multi-site study random assignment determines if prescribers to persons who suffer an opioid overdose fatal or nonfatal learn of this event intervention or practice usual-care control The AESOPS-2 trial will take place in 3 diverse health systems in the US - Northwestern Medicine AltaMed Health Services and The Childrens Clinic At Northwestern Medicine clinicians in the intervention group receive a letter notifying them of their patients fatal or nonfatal ED overdose At AltaMed Health Services and The Childrens Clinic clinicians in the intervention group receive a letter notifying them of their patients nonfatal ED overdose The primary outcome is the change in clinician weekly milligram morphine equivalent MME dose prescribed in 6-month periods before and after receiving the letter The secondary outcome is the change in the proportion of patients prescribed at least 50 daily MME Group differences in these outcomes will be compared using an intent-to-treat difference-in-differences framework with a mixed-effects regression model to estimate clinician MME weekly dose The AESOPS-2 trial will provide new knowledge about whether increasing prescribers awareness of patients opioid-related overdoses leads to a reduction in opioid prescribing Additionally this trial may better inform how to reduce opioid use disorder and opioid overdoses by lowering unnecessary population exposure to these drugs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R33AG057395 | NIH | None | httpsreporternihgovquickSearchR33AG057395 |