Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04753515
Status:
COMPLETED
Last Update Posted:
2022-11-30
First Post:
2021-02-10
Brief Title:
Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation
Sponsor:
Sixth Affiliated Hospital Sun Yat-sen University
Organization:
Sixth Affiliated Hospital Sun Yat-sen University
Study Overview
Official Title:
Comparison Between Dexmedetomidine and Propofol for Sedation When Combined With Midazolam and Remifentanil During Awake Endotracheal Intubation A Randomized Double-blind Controlled Study
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to compare the sedation effect of dexmedetomidine and propofol when they are both combined with midazolam and remifentanil during awake endotracheal intubation
Detailed Description:
Awake intubation is one of the best strategy guaranteed by the American Society of Anesthesiologists ASA guidelines for the management of patients with anticipated difficult airways Hemodynamic stability optimal intubating conditions patients comfort amnesia and preservation of patents spontaneous respiration are critical for awake intubation Sedation is one of the key elements for this technique Intravenous midazolam propofol dexmedetomidine and remifentanil are commonly used as sedatives during awake intubation These agents are not preferred to be used alone but in combination with each other for the purpose of minimizing their respective side effects The aim of this randomized controlled trial is to compare the safety and effectiveness of dexmedetomidine versus propofol for sedation during awake endotracheal intubation when they are both combined with midazolam and remifentanil
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None