Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04759742
Status:
COMPLETED
Last Update Posted:
2023-08-15
First Post:
2021-02-07
Brief Title:
The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery
Sponsor:
Yanchao Yang
Organization:
Shengjing Hospital
Study Overview
Official Title:
The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery
Status:
COMPLETED
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Fast-track Surgery FTS refers to the application of various proven effective methods in perioperative period to reduce stress and complications and accelerate the recovery of patientsNowadays FTS has been successfully applied in clinical practiceFTS truly embodies the concept of patient-centered and the direction of medical development
Lower limb joint damage the meniscus and patellar ligament etc is the joint movement orthopedic common disease often characterized by joint swelling pain sports relaxation instability thigh muscle atrophy most cant continue to pursue the original movement even unbend and flexor limited activity result in patients with walking difficulties serious impact on the patients quality of lifePractice has proved that minimally invasive surgery under arthroscopy is the best way to treat such injuries According to literature reports the average hospital stay after arthroscopy is 57 days while successful application of FTS can shorten it to 23 days
Anesthesia plays an important role in the process of FTSCompared with general anesthesia intra-spinal anesthesia can effectively reduce the incidence of postoperative complications in patients such as ventilator-related lung injury deep vein thrombosis cardiovascular and cerebrovascular accidents and acute renal failureRopivacaine is a long-acting amide local anesthetic Compared with bupivacaine it is more and more widely used in spinal anesthesia due to its advantages of lower degree of motor nerve block and weaker toxicity to central nervous system and cardiacHowever the optimal dosage of ropivacaine for arthroscopic surgery is still unclear Conventional dosage makes patients unable to move 2-4h after surgery and unable to urinate autonomically Therefore this study aims to optimize the dosage of ropivacaine for spinal anesthesia and enable patients to recover motor function at an early stage
Lower limb joint damage the meniscus and patellar ligament etc is the joint movement orthopedic common disease often characterized by joint swelling pain sports relaxation instability thigh muscle atrophy most cant continue to pursue the original movement even unbend and flexor limited activity result in patients with walking difficulties serious impact on the patients quality of lifePractice has proved that minimally invasive surgery under arthroscopy is the best way to treat such injuries According to literature reports the average hospital stay after arthroscopy is 57 days while successful application of FTS can shorten it to 23 days
Anesthesia plays an important role in the process of FTSCompared with general anesthesia intra-spinal anesthesia can effectively reduce the incidence of postoperative complications in patients such as ventilator-related lung injury deep vein thrombosis cardiovascular and cerebrovascular accidents and acute renal failureRopivacaine is a long-acting amide local anesthetic Compared with bupivacaine it is more and more widely used in spinal anesthesia due to its advantages of lower degree of motor nerve block and weaker toxicity to central nervous system and cardiacHowever the optimal dosage of ropivacaine for arthroscopic surgery is still unclear Conventional dosage makes patients unable to move 2-4h after surgery and unable to urinate autonomically Therefore this study aims to optimize the dosage of ropivacaine for spinal anesthesia and enable patients to recover motor function at an early stage
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None