Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04750980
Status:
COMPLETED
Last Update Posted:
2021-07-27
First Post:
2021-02-08
Brief Title:
Microbiota and Allergy
Sponsor:
Federico II University
Organization:
Federico II University
Study Overview
Official Title:
Microbiota as Potential Target for Innovative Preventive and Therapeutic Strategies for Food Allergy
Status:
COMPLETED
Status Verified Date:
2021-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MATFA I
Brief Summary:
Food allergy derives from a dysregulation of oral tolerance mechanisms Studies suggest a crucial role for gut microbiota in oral tolerance development An altered composition of gut microbiota results in an unbalanced local and systemic immune response to food allergens There are qualitative and quantitative differences in gut microbiota composition in children with food allergy Preliminary results of MATFA study demonstrated gut microbiota in allergic childrenThese findings support the pivotal role of the gut microbiota in the pathogenesis of allergic diseases and may open new strategies in the development of innovative preventive and therapeutic approaches
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None