Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:57 PM
Study NCT ID:
NCT04759755
Status:
COMPLETED
Last Update Posted:
2024-02-06
First Post:
2021-02-13
Brief Title:
Circadian Timing Information Processing and Energy Balance Study
Sponsor:
University of Utah
Organization:
University of Utah
Study Overview
Official Title:
Circadian and Sleep Pathways to Cardiometabolic Disease Risk Role of Neurobehavioral Processes
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TIME
Brief Summary:
This study design will test biological and behavioral mechanisms in the cross-sectional analyses and determine the prospective effects of circadian alignment and sleep on changes in cardiometabolic risk factors
Detailed Description:
The goal of this study is to determine how sleep and circadian rhythm alignment contribute to neurobehavioral and behavioral mechanisms of cardiometabolic risk The investigators propose that circadian misalignment which is more common among individuals with late sleep timing leads to increased consumption of energy denseprepared foods and to decreased insulin sensitivity Short sleep duration and neurobehavioral measures ie delay discounting may moderate these associations thus exacerbating cardiometabolic risk factors There is evidence for a direct biological link between circadian misalignment and insulin resistance and for a relationship that is mediated through changes in eating behaviors Insulin resistance and increased caloric intake over time lead to increased BMI and body fat
In this study the investigators will conduct cross-sectional and longitudinal analyses to determine biological and behavioral mechanisms that link circadian alignment and sleep duration to changes in cardiometabolic risk over 1 year This study will identify individual differences that predict risk for cardiometabolic disorders and suggest potential for sleep circadian and neurobehavioral interventions to reduce cardiometabolic risk
In this study the investigators will conduct cross-sectional and longitudinal analyses to determine biological and behavioral mechanisms that link circadian alignment and sleep duration to changes in cardiometabolic risk over 1 year This study will identify individual differences that predict risk for cardiometabolic disorders and suggest potential for sleep circadian and neurobehavioral interventions to reduce cardiometabolic risk
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01HL141706-01A1 | NIH | None | httpsreporternihgovquickSearch1R01HL141706-01A1 |