Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04752748
Status:
COMPLETED
Last Update Posted:
2021-02-17
First Post:
2021-02-10
Brief Title:
Power Doppler in Hand Joints of Early RA Patients
Sponsor:
Federal University of São Paulo
Organization:
Federal University of São Paulo
Study Overview
Official Title:
Power Doppler in Hand Joints is a Predictor of Therapeutic Failure in Women With Early Rheumatoid Arthritis Naive for Treatment
Status:
COMPLETED
Status Verified Date:
2021-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It is a prospective case-control study with women diagnosed early rheumatoid arthritis Three therapeutic failures were considered failure 1 - to the first Disease-modifying antirheumatic drugs DMARDs methotrexate failure 2 - to the second DMARDs leflunomide and failure 3 - to the first immunobiological drugs adalimumab Ultrasound was performed bilaterally on the 2nd and 3rd metacarpophalangeal joints MCFs proximal interphalangeal joints IFPs and wrists US10 Ultrasound measurements qualitative and semi-quantitative evaluated 1 - inflammatory synovial and tenosynovial proliferation in gray scale and power Doppler 0-3 2 - joint damage bone erosion qualitative and semi-quantitative and cartilage damage qualitative and semi-quantitative Clinical and laboratory variables were also assessed blindly at baseline and after 12 24 e 48 weeks
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None