Ignite Creation Date:
2024-05-06 @ 3:46 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04744298
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-06-25
First Post:
2021-02-01
Brief Title:
Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection Paralysis and Proning Pathway
Sponsor:
University of Calgary
Organization:
University of Calgary
Study Overview
Official Title:
Identification and Treatment of Hypoxemic Respiratory Failure HRF and ARDS With Protection Paralysis and Proning TheraPPP Study
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Treatment of patients with Hypoxemic respiratory failure HRF and Acute Respiratory Distress Syndrome ARDS is complex Therapies that have been shown to save the lives of patients with HRF and ARDS are available but they are not always provided To reduce practice variation and improve adherence to evidence-informed therapies the investigators developed the Treatment of Hypoxemic Respiratory Failure and ARDS with Protection Paralysis and Proning TheraPPP Pathway
The overall objective of TheraPPP Pathway is to improve the quality of care for patients with HRF Implementation of the pathway across Alberta will test the effectiveness and implementation of the TheraPPP Pathway
The overall objective of TheraPPP Pathway is to improve the quality of care for patients with HRF Implementation of the pathway across Alberta will test the effectiveness and implementation of the TheraPPP Pathway
Detailed Description:
Hypoxemic respiratory failure HRF and ARDS are common conditions among patients admitted to the Intensive care unit ICU Treatment of these patients is complex Evidence based therapies that can improve survival exist however implementation is extremely inconsistent As a potential solution to this problem the investigators developed the Treatment of Hypoxemic Respiratory Failure HRF and ARDS with Protection Paralysis and Proning TheraPPP Pathway to reduce practice variation and improve adherence to evidence-informed therapy
The TheraPPP pathway is a comprehensive evidence-based stakeholder-informed pathway for the diagnosis and management of HRF The overall objective of the pathway is to improve the quality of care for patients with HRF The specific objectives are to evaluate
1 Effectiveness of the pathway A cost-effectiveness analysis is a secondary objective
2 Implementation of the pathway by conducting a process evaluation which will assess fidelity of the delivered interventions and clinician perceptions about the acceptability of the pathway
Mechanically ventilated patients admitted to any one of 17 adult ICUs in Alberta will receive the intervention One ICU Calgary is the setting for a pilot study NCT04070053
For data analysis the investigators will use chart abstraction to quantitatively assess the fidelity of the delivered intervention and surveys and focus groups to qualitatively assess clinician perceptions about the acceptability of the pathway Fidelity of the intervention will be tracked using process of care indicators that reflect the five key steps of the pathway
The TheraPPP pathway is a comprehensive evidence-based stakeholder-informed pathway for the diagnosis and management of HRF The overall objective of the pathway is to improve the quality of care for patients with HRF The specific objectives are to evaluate
1 Effectiveness of the pathway A cost-effectiveness analysis is a secondary objective
2 Implementation of the pathway by conducting a process evaluation which will assess fidelity of the delivered interventions and clinician perceptions about the acceptability of the pathway
Mechanically ventilated patients admitted to any one of 17 adult ICUs in Alberta will receive the intervention One ICU Calgary is the setting for a pilot study NCT04070053
For data analysis the investigators will use chart abstraction to quantitatively assess the fidelity of the delivered intervention and surveys and focus groups to qualitatively assess clinician perceptions about the acceptability of the pathway Fidelity of the intervention will be tracked using process of care indicators that reflect the five key steps of the pathway
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None