Ignite Creation Date:
2024-05-06 @ 3:45 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04743193
Status:
COMPLETED
Last Update Posted:
2021-09-01
First Post:
2021-02-02
Brief Title:
Different Low-flow Sevoflurane Anesthesia Techniques
Sponsor:
Kocaeli Derince Education and Research Hospital
Organization:
Kocaeli Derince Education and Research Hospital
Study Overview
Official Title:
Comparison of the Consumption of Sevoflurane in Two Different Concentrations and Two Different Currents During the Initial Period of Anesthesia in Patients Undergoing General Anesthesia With Minimal Flow
Status:
COMPLETED
Status Verified Date:
2021-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
After reaching 1 MAC level with 4 lt min fresh gas flow and 25 sevoflurane concentration in the initial stage in 35 patients anesthesia maintenance will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration with the target of 1 MAC For 35 patients after reaching 1 MAC level with 1 lt min fresh gas flow and 8 sevoflurane concentration in the initial phase maintenance of anesthesia will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration targeting 1 MAC
Detailed Description:
The primary aim of this study is to compare the instantaneous and total consumption of sevoflurane using 2 different concentrations and different minute fresh gas flow to fill the system in the initial phase of anesthesia Its secondary purpose is to compare the depth of anesthesia and hemodynamic parameters between the two groups
A total of 70 patients between the ages of 18-65 will be included in the studyin 25 sevoflurane grup After reaching 1 MAC level with 4 lt min fresh gas flow and 25 sevoflurane concentration in the initial stage in 35 patients anesthesia maintenance will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration with the target of 1 MAC in sevoflurane 8 group for 35 patients after reaching 1 MAC level with 1 lt min fresh gas flow and 8 sevoflurane concentration in the initial phase maintenance of anesthesia will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration with the target of 1 MAC The depth of anesthesia for both groups will be measured by the Bispectral Index BIS BIS values between 40 and 60 are appropriate values for general anesthesia for this value 1 MAC sevoflurane inhalation anesthesia and remifentanil infusion 01-03mcg kg min will be used
A total of 70 patients between the ages of 18-65 will be included in the studyin 25 sevoflurane grup After reaching 1 MAC level with 4 lt min fresh gas flow and 25 sevoflurane concentration in the initial stage in 35 patients anesthesia maintenance will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration with the target of 1 MAC in sevoflurane 8 group for 35 patients after reaching 1 MAC level with 1 lt min fresh gas flow and 8 sevoflurane concentration in the initial phase maintenance of anesthesia will be continued with 05 lt min fresh gas flow and 2 -4 sevoflurane concentration with the target of 1 MAC The depth of anesthesia for both groups will be measured by the Bispectral Index BIS BIS values between 40 and 60 are appropriate values for general anesthesia for this value 1 MAC sevoflurane inhalation anesthesia and remifentanil infusion 01-03mcg kg min will be used
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None