Ignite Creation Date:
2024-05-06 @ 3:45 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04749199
Status:
UNKNOWN
Last Update Posted:
2021-02-15
First Post:
2020-12-03
Brief Title:
Enhanced Mirror Therapy for Improving Brain Reorganization and Function in Stroke
Sponsor:
The Hong Kong Polytechnic University
Organization:
The Hong Kong Polytechnic University
Study Overview
Official Title:
Enhanced Mirror Therapy for Improving Brain Reorganization and Function in Stroke A Pilot Randomized Controlled Trial With Economic Evaluation
Status:
UNKNOWN
Status Verified Date:
2021-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This research aims to test the methodological procedures and obtain preliminary results regarding the therapeutic and cost-effectiveness of enhanced mirror therapy relative to standard mirror therapy for improving brain reorganization and upper limb function in individuals with stroke
Detailed Description:
Stroke is among the leading causes of mortality and disability worldwide Muscle weakness and other complications associated with stroke can result in decreased quality of life and significant declines in the activities of daily living Mirror therapy has been shown to have a moderate effect facilitating the functional recovery among individuals who have experienced a stroke A prototype for a computerized mirror therapy device was developed and found to be feasible Recently the investigators published a critical review and an activation likelihood estimation ALE meta-analysis analysing the widespread reports of brain activity associated with mirror therapy Observations using functional near-infrared spectroscopy fNIRS to evaluate a group of people with stroke n 14 and healthy volunteers n 18 revealed that performing complex tasks during the mirror therapy paradigm enhanced top-down motor facilitation in the ipsilesionalipsilateral hemisphere relative to the moving limb An important next step in this series of studies is to evaluate the training effects associated with the performance of complex tasks during mirror therapy among stroke patients using the designed computerized mirror therapy device to deliver the enhanced mirror therapy training The results of this study will help the investigators to understand the underlying mechanisms through which mirror therapy facilitates motor rehabilitation and will add to the body of literature describing the best evidence-based practices for mirror therapy during stroke rehabilitation The investigators propose a pilot study n 30 to test the methodological procedures and obtain preliminary results for a fully powered randomized controlled trial RCT combined with economic evaluation to compare the therapeutic and cost-effectiveness between standard mirror therapy and enhanced complex task and blurred image mirror therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None