Ignite Creation Date:
2024-05-06 @ 3:45 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04749212
Status:
UNKNOWN
Last Update Posted:
2022-09-06
First Post:
2021-01-18
Brief Title:
Perioperative Troponin I and NT Pro-BNP in Lung Resection
Sponsor:
Hospital Universitari Vall dHebron Research Institute
Organization:
Hospital Universitari Vall dHebron Research Institute
Study Overview
Official Title:
Incidence and Clinical Relevance of Perioperative Elevation of Troponin I and N- Terminal Pro-Brain Natriuretic Peptide in Patients Undergoing Lung Resection
Status:
UNKNOWN
Status Verified Date:
2022-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
After lung resection troponin elevation may be regulated by mechanisms other than myocardial ischemia Perioperative natriuretic peptides measurement may help identify changes in ventricular function during thoracic surgery Integrating both cardiac biomarkers may improve the predictive value for cardiovascular complications after lung resection
Detailed Description:
Objectives To evaluate the incidence and magnitude of perioperative N-terminal pro brain natriuretic peptide NT-proBNP and high-sensitivity troponin I Tn I elevation in patients undergoing pulmonary resection and its predictive value for cardiovascular complications Methodology Prospective multicenter observational cohort study in patients 45 years undergoing elective thoracic surgery for lung resection Cardiac biomarkers Tn I and NT-proBNP will be measured preoperatively and at postoperative days 1 and 2 Risk score for major cardiovascular postoperative complications will be calculated depending of both biomarkers perioperative changes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None