Ignite Creation Date:
2024-05-06 @ 3:45 PM
Last Modification Date:
2024-10-26 @ 1:56 PM
Study NCT ID:
NCT04744987
Status:
COMPLETED
Last Update Posted:
2022-08-03
First Post:
2021-02-04
Brief Title:
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia
Sponsor:
Hospital San Carlos Madrid
Organization:
Hospital San Carlos Madrid
Study Overview
Official Title:
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia
Status:
COMPLETED
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Retrospective study that analyzes the changes in serum creatinine as a tool to correctly classify the volemic status volemic status euvolemia vs hypovolemia of the patients with hyponatremia
Detailed Description:
This study evaluates the usefulness of the changes in serum creatinine in differentiating between euvolemia and hypovolemia in hyponatremic patients Changes in serum creatinine were retrospectively analyzed The latter was calculated subtracting the serum creatinine value of eunatremia from that of hyponatremia and was categorized as an increase when it was positive or decreaseno change when it was negative or equal to zero The percentual change in serum creatinine was also calculated
Two groups of patients were selected for the current study First group was conformed by patients with hypovolemic hyponatremia and second group by patients with euvolemic hyponatremia Data from eunatremia as well as the hyponatremic episode were collected Both groups were matched in Receiver operating characteristic curve analyzes where both arithmetical and percentual changes in serum creatinine were assessed and cut-off points were selected for an additional Odd Ratio analysis
Two groups of patients were selected for the current study First group was conformed by patients with hypovolemic hyponatremia and second group by patients with euvolemic hyponatremia Data from eunatremia as well as the hyponatremic episode were collected Both groups were matched in Receiver operating characteristic curve analyzes where both arithmetical and percentual changes in serum creatinine were assessed and cut-off points were selected for an additional Odd Ratio analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None