Ignite Creation Date:
2024-05-05 @ 5:18 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00421486
Status:
UNKNOWN
Last Update Posted:
2016-01-21
First Post:
2007-01-10
Brief Title:
Oral Human Papillomavirus Infection in HIV-infected Men
Sponsor:
Deutsche Luft und Raumfahrt
Organization:
Deutsche Luft und Raumfahrt
Study Overview
Official Title:
Incidence Prevalence Spectrum of HPV-types and Viral Load Determination of High-risk Human Papillomavirus Infection of the Oral Cavity in HIV-infected Men Who Have Sex With Men
Status:
UNKNOWN
Status Verified Date:
2016-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Human papillomavirus HPV-infection belong to the most common sexually transmitted diseases worldwide HIV-infected men having sex with men MSM are strongly associated with a higher prevalence of genitoanal HPV-infection and perianal HPV-infections have been detected in up to 90 of HIV-positive men The data concerning the incidence of oral HPV-infection in HIV-positive men especially in the era of highly antiretroviral therapy are conflicting Thus this prospective study mainly focuses on the incidence and prevalence of oral HPV-infection spectrum of HPV-types and oral high-risk HPV viral load in HIV-positive men
Detailed Description:
Human papillomavirus HPV-infection belong to the most common sexually transmitted diseases worldwide Estimated prevalences of subclinical genital HPV-infection in the immunocompetent sexually active population range from 10 to above 50 Genetic or iatrogenic immunosuppression is known to play a decisive role in the initiation of a variety of cutaneous neoplasias and their precursor lesions In this context HPV-associated anogenital malignancies occur with high frequency in patients with HIV-infection In several studies perianal HPV-infections have been detected in up to 90 of HIV-positive men and a high incidence of anal dysplasia has been reported in these patients The data concerning the incidence of oral HPV-infection in HIV-positive men especially in the era of highly antiretroviral therapy are conflicting Thus this prospective study mainly focuses on the incidence and prevalence of oral HPV-infection spectrum of HPV-types and oral high-risk HPV viral load in HIV-positive men
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None