Ignite Creation Date:
2024-05-06 @ 3:44 PM
Last Modification Date:
2024-10-26 @ 1:55 PM
Study NCT ID:
NCT04733235
Status:
COMPLETED
Last Update Posted:
2023-01-03
First Post:
2021-01-17
Brief Title:
the Effect of Endometrial Compaction Caused by Progesterone Effect on Pregnancy Outcomes
Sponsor:
Akdeniz University
Organization:
Akdeniz University
Study Overview
Official Title:
The Effect of Progesterone Induced Endometrial Compaction on Pregnancy Outcomes in Frozen-thawed Embryo Transfer at the Blastocyst Stage
Status:
COMPLETED
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this prospective cohort study is to assess the effect of endometrial compaction caused by progesterone effect on pregnancy outcomes
Detailed Description:
For a pregnancy to occur the embryo must implant in a receptive endometrium during the window of implantation which is thought to occur from day 22 to 24 of an idealized 28-day cycle Early studies have suggested that assessing endometrial thickness with the use of ultrasound may be an alternative to invasive techniques such as endometrial biopsy for attempting to determine a receptive endometrium for frozen-thawed embryo transfer FET
A preovulatory endometrial thickness of 7 mm or more is considered to be the cutoff for endometrial receptivity below which many physicians would cancel an embryo transfer However in most studies in the literature endometrial thickness was measured either on the day of hCG in fresh embryo transfer cases or on the last day of estrogen treatment in thawed embryo transfers There are a limited number of studies evaluating the luteal period embryo transfer day and endometrial thickness
Accordingly in this prospective cohort study is to assess the effect of endometrial compaction caused by progesterone effect on pregnancy outcomes
A preovulatory endometrial thickness of 7 mm or more is considered to be the cutoff for endometrial receptivity below which many physicians would cancel an embryo transfer However in most studies in the literature endometrial thickness was measured either on the day of hCG in fresh embryo transfer cases or on the last day of estrogen treatment in thawed embryo transfers There are a limited number of studies evaluating the luteal period embryo transfer day and endometrial thickness
Accordingly in this prospective cohort study is to assess the effect of endometrial compaction caused by progesterone effect on pregnancy outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None