Ignite Creation Date:
2024-05-06 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 1:55 PM
Study NCT ID:
NCT04732754
Status:
UNKNOWN
Last Update Posted:
2021-08-20
First Post:
2021-01-27
Brief Title:
Effect of Cocoa Supplementation and Aerobic Exercise on Pressure Parameters
Sponsor:
Instituto de Cardiologia do Rio Grande do Sul
Organization:
Instituto de Cardiologia do Rio Grande do Sul
Study Overview
Official Title:
Effect of Cocoa Supplementation and Aerobic Exercise on Central Pressure and Arterial Stiffness Parameters in Physically Inactive Middle-aged Individuals
Status:
UNKNOWN
Status Verified Date:
2021-08
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study evaluates the cocoa supplementation and aerobic exercise on central pressure and arterial stiffness parameters in physically inactive middle-aged individuals
500mg capsules will be offered to all patients Of these half will offer the content of 500mg of cocoa per capsule or placebo capsules The placebo will contain a pharmacologically inert substance microcrystalline cellulose of the same color A half will start 50 aerobic training 3 timesweek while the other half will continue without exercise
500mg capsules will be offered to all patients Of these half will offer the content of 500mg of cocoa per capsule or placebo capsules The placebo will contain a pharmacologically inert substance microcrystalline cellulose of the same color A half will start 50 aerobic training 3 timesweek while the other half will continue without exercise
Detailed Description:
Cardiovascular diseases CVDs are the number one cause of death in the world more people die annually from CVDs than from any other cause The arterial hypertension is one of the main predictors of CVDs The number of adults with high blood pressure increased from 594 million in 1975 to 113 billion in 2015 WHO 2020
Due to the great increase in Hypertension around the world new technological ways of assessing pressure have been discussed in the clinical setting not only peripheral but also central
In this sense the applanation tonometry of different arteries carotid and radial the analysis of pulses by various algorithms and the ability to estimate the shape of the pulse wave in the descending aorta root has been gaining prominence
Flavonoids are a group of polyphenol compounds found in plants The possible benefits from these compounds are related to cardiovascular health through specific actions on the artery wall Prospective studies have shown that flavonoids can improve arterial stiffness measured by Pulse Wave Velocity PWV
Physical exercise can intensifies organic functioning in different systems oh human body including the cardiovascular Studies has shown that chronic adaptations of pshysical exercise can improve arterial stiffness and central blood pressure parameters
Due to the great increase in Hypertension around the world new technological ways of assessing pressure have been discussed in the clinical setting not only peripheral but also central
In this sense the applanation tonometry of different arteries carotid and radial the analysis of pulses by various algorithms and the ability to estimate the shape of the pulse wave in the descending aorta root has been gaining prominence
Flavonoids are a group of polyphenol compounds found in plants The possible benefits from these compounds are related to cardiovascular health through specific actions on the artery wall Prospective studies have shown that flavonoids can improve arterial stiffness measured by Pulse Wave Velocity PWV
Physical exercise can intensifies organic functioning in different systems oh human body including the cardiovascular Studies has shown that chronic adaptations of pshysical exercise can improve arterial stiffness and central blood pressure parameters
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None