Ignite Creation Date:
2024-05-06 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04723043
Status:
COMPLETED
Last Update Posted:
2021-10-14
First Post:
2021-01-20
Brief Title:
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
Sponsor:
Sisli Hamidiye Etfal Training and Research Hospital
Organization:
Sisli Hamidiye Etfal Training and Research Hospital
Study Overview
Official Title:
The Effect of Pressure Controlled and Volume Controlled Ventilation Modes on Cerebral Oxymetry and Blood Gases In Laparoscopic Cholecystectomy Operations
Status:
COMPLETED
Status Verified Date:
2021-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In laparoscopic cholecystectomy method Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards a decrease in lungs volume and its compliance an increase in the airway resistance mismatch between the atelectasis and the ventilation perfusion Although there are numerous studies in laparoscopic surgery only a few of them investigate the effects of laparoscopic surgery on the cardiopulmonary and the respiratory mechanics The investigator aimed To examine the effects of pressure-controlled and volume-controlled ventilation modes on cerebral oximetry and blood gases in laparoscopic cholecystectomy operations
Detailed Description:
Since the laparoscopic methods have been introduced to the surgical operations laparoscopic cholecystectomy has become the golden standard in gall bladder surgical treatments In this method carbon dioxide CO2 pneumoperitoneum method is used to achieve the desired surgical and visual conditions Alongside the advantages of the Laparoscopic cholecystectomy method eg shortening the patients length of stay at the hospital minimal postoperative pain and rapid recovery it has various intraabdominal pressure related systemic disadvantages Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards a decrease in lungs volume and its compliance an increase in the airway resistance mismatch between the atelectasis and the ventilation perfusion Various ventilation strategies have been introduced to increase arterial oxygenation functional residual capacity FRC and the lung compliance Recent studies demonstrates that pressure-controlled mechanical ventilation is superior to volume-controlled mechanical ventilation in providing arterial and tissue oxygenation
Although there are numerous studies in laparoscopic surgery only a few of them investigate the effects of laparoscopic surgery on the cardiopulmonary and the respiratory mechanics Several experimental and clinical studies describe that the cardiovascular effects of the high intraabdominal pressure and the CO2 insufflation is complex In fact the results are linked to the studied patients population the lungs position and its volume As it is known in laparoscopic surgeries the oxygenation in cerebral tissue decreases as the intraabdominal pressure increases At present bispectral index BIS electroencephalography EEG auditory evoke potential AEP and several others and functional NIRS fNIRS are used to measure cerebral oxygenation and anaesthetic depth NIRS monitorisation makes use of the combined effects of the transmission the reflection the dispersion and the absorption of light It can also measure the oxygen saturation in tissues that does not have pulsatile circulation The investigator aimed To examine the effects of pressure-controlled and volume-controlled ventilation modes on cerebral oximetry and blood gases in laparoscopic cholecystectomy operations
Although there are numerous studies in laparoscopic surgery only a few of them investigate the effects of laparoscopic surgery on the cardiopulmonary and the respiratory mechanics Several experimental and clinical studies describe that the cardiovascular effects of the high intraabdominal pressure and the CO2 insufflation is complex In fact the results are linked to the studied patients population the lungs position and its volume As it is known in laparoscopic surgeries the oxygenation in cerebral tissue decreases as the intraabdominal pressure increases At present bispectral index BIS electroencephalography EEG auditory evoke potential AEP and several others and functional NIRS fNIRS are used to measure cerebral oxygenation and anaesthetic depth NIRS monitorisation makes use of the combined effects of the transmission the reflection the dispersion and the absorption of light It can also measure the oxygen saturation in tissues that does not have pulsatile circulation The investigator aimed To examine the effects of pressure-controlled and volume-controlled ventilation modes on cerebral oximetry and blood gases in laparoscopic cholecystectomy operations
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None