Ignite Creation Date:
2024-05-06 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 1:55 PM
Study NCT ID:
NCT04725539
Status:
UNKNOWN
Last Update Posted:
2022-03-25
First Post:
2021-01-08
Brief Title:
Hypoxia Pre-conditioning and Mountain Sport
Sponsor:
Institute of Mountain Emergency Medicine
Organization:
Institute of Mountain Emergency Medicine
Study Overview
Official Title:
Effects of Hypoxia Pre-conditioning on Physiological Responses During Mountain Sport Activities in Persons With a History of Coronary Artery Disease
Status:
UNKNOWN
Status Verified Date:
2022-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Hyx-PRE-Spo
Brief Summary:
Mountain sport activities as for example hiking or skiing may involve the risk of adverse health events especially in older people not accustomed to the specific mountain sport at altitude or people with pre-existing health issues Increased activation of the sympathetic nervous system and abrupt changes in heart rate and blood pressure are thought to trigger these adverse effects Preventive measures include regular physical activity ie training and adequate medical treatment Hypoxia pre-adaptation eg pre-adapt one night at moderate altitude and pre-conditioning eg intermittent hypoxia IH training which was shown to lead to some favorable sympathetic nervous system ventilatory and metabolic adaptations and additionally exerts anti-inflammatory action could be hypothesized of being a further preventive measure The aim of this research project is to investigate whether intermittent hypoxia pre-conditioning or sleeping one night at altitude ie current recommendation before practicing mountain leisure sports in the elderly is able to increase oxygen saturation during passive hypoxia exposure and during simulated hiking and skiing at altitude Additionally it is aimed to investigate whether such procedure reduces the physiological responses ie heart rate its variability and blood pressure including baroreflex sensitivity responses as well as metabolic ventilatory inflammatory and redox responses during these activities
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None