Ignite Creation Date:
2024-05-06 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04723446
Status:
COMPLETED
Last Update Posted:
2023-09-14
First Post:
2021-01-05
Brief Title:
Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2 Viral Load in the Saliva
Sponsor:
Queen Mary University of London
Organization:
Queen Mary University of London
Study Overview
Official Title:
Efficacy of Three Antimicrobial Mouthwashes in Reducing SARS-CoV-2 Viral Load in the Saliva of Patients Diagnosed With COVID-19 A Pilot Study
Status:
COMPLETED
Status Verified Date:
2021-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COVID-19
Brief Summary:
This is a single-blind parallel-group randomized pilot study designed to evaluate and compare the efficacy of 3 different mouthwashes containing 02 Chlorhexidine digluconate 15 Hydroxide peroxide or Cetylpyridinium chloride in reducing Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 viral load in the saliva of COVID-19 positive patients at different time-points
A convenient sample of up to 40 COVID-19 positive patients diagnosed via test andor presenting COVID-19 clinical symptoms will be identified in the inpatients andor outpatient clinics at the Newham University Hospital and at The Royal London Hospital Barts Health National Health Service NHS Trust United Kingdom UK
The study will consist of one visit Unstimulated saliva samples will be collected from all COVID-19 positive patients before and at 30 minutes 1 2 and 3 hours after mouth rinsing Group 1-3 or no rinsing Group 4 Viral load analysis of saliva samples in the different time-points will be then assessed by Reverse Transcription quantitative PCR RT- qPCR
A convenient sample of up to 40 COVID-19 positive patients diagnosed via test andor presenting COVID-19 clinical symptoms will be identified in the inpatients andor outpatient clinics at the Newham University Hospital and at The Royal London Hospital Barts Health National Health Service NHS Trust United Kingdom UK
The study will consist of one visit Unstimulated saliva samples will be collected from all COVID-19 positive patients before and at 30 minutes 1 2 and 3 hours after mouth rinsing Group 1-3 or no rinsing Group 4 Viral load analysis of saliva samples in the different time-points will be then assessed by Reverse Transcription quantitative PCR RT- qPCR
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None