Ignite Creation Date:
2024-05-06 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 1:54 PM
Study NCT ID:
NCT04713436
Status:
COMPLETED
Last Update Posted:
2021-01-19
First Post:
2021-01-11
Brief Title:
The Effects of Antibiotic Combinations on Stem Cells
Sponsor:
Eskisehir Osmangazi University
Organization:
Eskisehir Osmangazi University
Study Overview
Official Title:
The Effects of Antibiotic Combinations on Mesenchymal Stem Cells Derived From Apical Papilla
Status:
COMPLETED
Status Verified Date:
2021-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was to evaluate the indirect effects of antibiotic combinations SCAP viability proliferation and apoptosis of the cells were evaluated Osteocalcin BGLAP dentin sialo phosphoprotein DSPP and alkaline phosphatase ALPP gene expression levels were also evaluated
Detailed Description:
The purpose of this study was to evaluate the indirect effects of triple TAP- ciprofloxacin metronidazole and minocycline double DAP- ciprofloxacin and metronidazole and modified triple antibiotic pastes mTAP- ciprofloxacin metronidazole and cefaclor on mesenchmal stem cells derived from apical papilla SCAP SCAP were isolated from the impacted third molar teeth of the young adults TAP DAP and mTAP treatment 14-day medication and 28-day medication were applied on SCAP and viability proliferation and apoptosis of the cells were evaluated after four weeks Osteocalcin BGLAP dentin sialo phosphoprotein DSPP and alkaline phosphatase ALPP gene expression levels were also evaluated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None