Ignite Creation Date:
2024-05-05 @ 5:17 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00423111
Status:
UNKNOWN
Last Update Posted:
2007-09-21
First Post:
2007-01-15
Brief Title:
Correlation Between Cognitive Functions and MRI in Multiple Sclerosis
Sponsor:
Sheba Medical Center
Organization:
Sheba Medical Center
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2007-09
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether there is a correlation between cognitive functions and volume of specific brain area measured in MRI of multiple sclerosis patients
Detailed Description:
Recent literature suggests that multiple sclerosis is accompanied by significant deficits in cognitive performance The origin of these cognitive deficits is not known since the severity of cognitive deficits was not found to be correlated with disease parameters such as duration lesion load or disease intensity as measured on standard scales eg EDSS The research hypothesis we plan to test is that the individual intensity of cognitive deficits is correlated with degeneration of specific neuronal structures related to cognitive performance such as the hippocampus and prefrontal cortex
To test this hypothesis we plan to perform volumetric measurements of such regions on MRI scans obtained from MS patients during the course of their clinical evaluation and attempt to correlate those with the results of neuropsychological tests performed by the same subjects around the time of MRI scanning
To test this hypothesis we plan to perform volumetric measurements of such regions on MRI scans obtained from MS patients during the course of their clinical evaluation and attempt to correlate those with the results of neuropsychological tests performed by the same subjects around the time of MRI scanning
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None